Article
The -137G>C polymorphism in interleukin-18 promoter region and cancer risk: evidence from a meta-analysis of 21 studies.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2013
Liang Tie-Jun, Ma Hui, Wang Cong-Xiao, Liu Yin-Rong, Wang Xing-Guo
Abstract excerpt
Interleukin-18 (IL-18) is a key cytokine responsible for immune response and involved in the process of cancer development. The association of -137G>C polymorphism in the promoter region of IL-18 with cancer risk is still elusive based on current genetic association studies. We performed this meta-analysis to determine whether the -137G>C polymorphism is associated with cancer risk. A comprehensive search was...
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