Article
Effects of interleukin-18 promoter (C607A and G137C) gene polymorphisms and their association with oral squamous cell carcinoma (OSCC) in northern India.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2014
Singh Prithvi Kumar, Ahmad Mohd Kaleem, Kumar Vijay, Hussain Syed Rizwan, Gupta Rajni, Jain Amita, Mahdi Abbas Ali, Bogra Jaishri, Chandra Girish
Abstract excerpt
Interleukin-18 (IL-18) is one of the immunomodulatory cytokines that plays an important role in cellular functions against tumor development and progression. IL-18 (-607) C/A and (-0137) G/C gene promoter polymorphisms and their haplotypes variants are associated with risk of various cancers. We evaluated a possible association of IL-18 (-607) C/A and (-137) G/C gene promoter polymorphisms in the susceptibility...
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