Article
Association of interleukin 18-607A/C and -137C/G polymorphisms with oxidative stress in renal transplant recipients.
Renal failure - 1 Jun 2016
Davran Fatih, Yilmaz Vural Taner, Erdem Bilge Karatoy, Gultekin Meral, Suleymanlar Gultekin, Akbas Halide
Abstract excerpt
Objectives IL-18 mediates various inflammatory and oxidative responses including renal injury, fibrosis, and graft rejection. It has been reported that the promoter -607 and -137 polymorphisms of IL-18 influence the level of IL-18. This prospective observational study investigated the association between oxidative stress with IL-18-607 and -137 polymorphisms in renal transplant recipients. Patients and methods...
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