Article
Identification of a ceRNA Network Regulating Malignant Transformation of Isocitrate Dehydrogenase Mutant Astrocytoma: An Integrated Bioinformatics Study.
Current computer-aided drug design - 1 Jan 2025
Cui Yaqian, Zheng Hongquan, Zhou Zhengwei, Liu Suo, Shen Mingxue, Qiu Runze, Zhang Xiong, Li Yingbin, Fan Hongwei
Abstract excerpt
INTRODUCTION: Astrocytoma is the most common glioma, accounting for about 65% of glioblastoma. Its malignant transformation is also one of the important causes of patient mortality, making it the most prevalent and difficult to treat in primary brain tumours. However, little is known about the underlying mechanisms of this transformation. METHODS: In this study, we established a ceRNA network to screen out the...
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