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Long non-coding RNA in glioma: novel genetic players in temozolomide resistance

15 Feb 2023

Abstract excerpt

Glioma is the most common primary malignant brain tumor in adults and accounts for approximately 80% of brain and central nervous system tumors. In 2021, the World Health Organization (WHO) published a new taxonomy for glioma based on its histological features and molecular alterations. Isocitrate dehydrogenase (IDH) catalyzes the decarboxylation of isocitrate, a critical metabolic reaction in energy generation...

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PMID: 36819921
DOI: 10.1080/19768354.2023.2175497

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