Article
IDH1 mutation-associated long non-coding RNA expression profile changes in glioma.
Journal of neuro-oncology - 1 Nov 2015
Zhang Xiao-Qin, Kiang Karrie Mei-Yee, Wang Yue-Chun, Pu Jenny Kan-Suen, Ho Amy, Cheng Stephen Yin, Lee Derek, Zhang Ping-De, Chen Jia-Jing, Lui Wai-Man, Fung Ching-Fai, Leung Gilberto Ka-Kit
Abstract excerpt
Isocitrate dehydrogenase 1 (IDH1) mutation is an important prognostic marker in glioma. However, its downstream effect remains incompletely understood. Long non-coding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis in a number of human malignancies, including glioma. Here, we investigated whether and how lncRNA expression profiles would differ between gliomas with or without IDH1 mutation....
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