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Article

scPAS: single-cell phenotype-associated subpopulation identifier.

Briefings in bioinformatics - 22 Nov 2024

Xie Aimin, Wang Hao, Zhao Jiaxu, Wang Zhaoyang, Xu Jinyuan, Xu Yan

Abstract excerpt

Despite significant advancements in single-cell sequencing analysis for characterizing tissue sample heterogeneity, identifying the associations between cell subpopulations and disease phenotypes remains a challenging task. Here, we introduce scPAS, a new bioinformatics tool designed to integrate bulk data to identify phenotype-associated cell subpopulations within single-cell data. scPAS employs a...

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Identifiers

PMID: 39681325
DOI: 10.1093/bib/bbae655
PMCID: PMC11649301

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