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Article

Identification of cell subpopulations associated with disease phenotypes from scRNA-seq data using PACSI.

BMC biology - 19 Jul 2023

Liu Chonghui, Zhang Yan, Gao Xin, Wang Guohua

Abstract excerpt

BACKGROUND: Single-cell RNA sequencing (scRNA-seq) has revolutionized the transcriptomics field by advancing analyses from tissue-level to cell-level resolution. Despite the great advances in the development of computational methods for various steps of scRNA-seq analyses, one major bottleneck of the existing technologies remains in identifying the molecular relationship between disease phenotype and cell...

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Identifiers

PMID: 37468850
DOI: 10.1186/s12915-023-01658-3
PMCID: PMC10354926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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