Article
Identifying phenotype-associated subpopulations through LP_SGL.
Briefings in bioinformatics - 22 Nov 2023
Li Juntao, Zhang Hongmei, Mu Bingyu, Zuo Hongliang, Zhou Kanglei
Abstract excerpt
Single-cell RNA sequencing (scRNA-seq) enables the resolution of cellular heterogeneity in diseases and facilitates the identification of novel cell types and subtypes. However, the grouping effects caused by cell-cell interactions are often overlooked in the development of tools for identifying subpopulations. We proposed LP_SGL which incorporates cell group structure to identify phenotype-associated...
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