Article

A statistical framework for disease classification with scRNA-Seq Data

2026-08-25

Abstract excerpt

Motivation Bulk RNA-sequencing based disease classification obscures cell-type specific signals by aggregating gene expression across heterogeneous tissues. Although single-cell RNA-seq tackles this limitation, summarizing and deriving patient-level predictors while retaining biological interpretability remains challenging. Standard sparse methods, such as lasso, often select arbitrary scattered gene sets without...

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Literature Corpus work: 1623f664-c36d-558d-8ec1-4306ecf60379
DOI: 10.64898/2026.08.21.746294

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