[Semi-rational design improves the catalytic activity of butyrylcholinesterase against ghrelin].

Abstract excerpt

Ghrelin, a hormone mainly produced and released by the stomach, has numerous functions, including releasing growth hormones, regulating appetite, and processing sugar and lipids. Researchers have made great efforts to study the relationship between ghrelin and metabolic diseases. It is believed that human butyrylcholinesterase (hBChE) could hydrolyze ghrelin to the inactive form (desacyl-ghrelin). However, the...

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• Butyrylcholinesterase
• Catalysis
• Escherichia coli
• Ghrelin
• Mutation