Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Novel Human Ghrelin Variant (In1-Ghrelin) and Ghrelin-O-Acyltransferase Are Overexpressed in Breast Cancer: Potential Pathophysiological Relevance

4 Aug 2011

Abstract excerpt

The human ghrelin gene, which encodes the ghrelin and obestatin peptides, contains 5 exons (Ex), with Ex1-Ex4 encoding a 117 amino-acid (aa) preproprotein that is known to be processed to yield a 28-aa (ghrelin) and/or a 23-aa (obestatin) mature peptides, which possess biological activities in multiple tissues. However, the ghrelin gene also encodes additional peptides through alternative splicing or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Biochemical Analysis and Sensing Techniques
Share to Regulation of Appetite and Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21829727
DOI: 10.1371/journal.pone.0023302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Novel Human Ghrelin Variant (In1-Ghrelin) and Ghrelin-O-Acyltransferase Are Overexpressed in Breast Cancer: Potential Pathophysiological RelevancePMID 21829727Read ↗

In1-ghrelin, a splice variant of ghrelin gene, is associated with the evolution and aggressiveness of human neuroendocrine tumors: Evidence from clinical, cellular and molecular parametersSemantic proximity Read ↗

Revised genomic structure of the human ghrelin gene and identification of novel exons, alternative splice variants and natural antisense transcriptsSemantic proximity Read ↗

The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressivenessSemantic proximity Read ↗

Expression and function of the ghrelin axis, including a novel preproghrelin isoform, in human breast cancer tissues and cell linesSemantic proximity Read ↗

Ghrelin gene‐related peptides: Multifunctional endocrine / autocrine modulators in health and diseaseSemantic proximity Read ↗

Beyond Hunger: Structure, Signaling and Systemic Roles of GhrelinSemantic proximity Read ↗

Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase (GOAT) is associated with anorexia nervosa.Semantic proximity Read ↗

Beyond Hunger: The Structure, Signaling, and Systemic Roles of Ghrelin.Semantic proximity Read ↗

Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC).Semantic proximity Read ↗

Cloning and characterization of the 5′-flanking region of the human ghrelin geneSemantic proximity Read ↗

Physiological role of ghrelin as revealed by the ghrelin and GOAT knockout mice.Semantic proximity Read ↗

Transgenic mice overexpressing ghrelin or ghrelin analog.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.