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Article

Modulation of the constitutive activity of the ghrelin receptor by use of pharmacological tools and mutagenesis.

Methods in enzymology - 1 Jan 2010

Mokrosiński Jacek, Holst Birgitte

Abstract excerpt

Ghrelin and its receptor are important regulators of metabolic functions, including appetite, energy expenditure, fat accumulation, and growth hormone (GH) secretion. The ghrelin receptor is characterized by an ability to signal even without any ligand present with approximately 50% of the maximally ghrelin-induced efficacy-a feature that may have important physiological implications. The high basal signaling can...

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PMID: 21036226
DOI: 10.1016/B978-0-12-381298-8.00003-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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