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Article

Unveiling therapeutic targets for spinal stenosis from genetic insights: a Mendelian randomization analysis.

Scientific reports - 24 Nov 2024

Fan Zhaopeng, Chen Bohong, Ding Le, Guo Hua

Abstract excerpt

Spinal stenosis is a commonly chronic spinal degenerative disease, which is a major cause of pain and dysfunction in the elderly. Mendelian randomization (MR) has been widely applied to repurpose licensed drugs and identify novel therapeutic targets. Consequently, we intended to identify new therapeutic targets for spinal stenosis and to analyze their possible mechanisms and potential side effects.We conducted...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 39582071
DOI: 10.1038/s41598-024-80697-4
PMCID: PMC11586425

Genes

DLK1
GFPT1
BMP6

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