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The causal association between type 2 diabetes and spinal stenosis: A Mendelian randomization analysis.

Medicine - 27 Sept 2024

Fan Zhaopeng, Chen Bohong, Ding Le, Guo Hua

Abstract excerpt

Spinal stenosis is a prevalent degenerative spinal disease and one of the main causes of pain and dysfunction in older adults. Substantial evidence indicates a potentially relevant association between type 2 diabetes mellitus (T2DM) and spinal stenosis. However, the causality between these 2 disorders remains unclear. Therefore, we intended to elucidate this relationship using Mendelian Randomization (MR)...

Topics

Humans
Mendelian Randomization Analysis
Diabetes Mellitus, Type 2
Spinal Stenosis
Genome-Wide Association Study
Body Mass Index
Risk Factors
Male
Causality
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39331863
DOI: 10.1097/MD.0000000000039894
PMCID: PMC11441963

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