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Article

Novel Insights Into the Causal Effects and Shared Genetics Between Body Fat and Parkinson Disease.

CNS neuroscience & therapeutics - 1 Nov 2024

Zhao Qian, Liu Dongming, Baranova Ancha, Cao Hongbao, Zhang Fuquan

Abstract excerpt

AIMS: Existing observational studies examining the effect of body fat on the risk of Parkinson disease (PD) have yielded inconsistent results. We aimed to investigate this causal relationship at the genetic level. METHODS: We employed two-sample Mendelian randomization (TSMR) to investigate the causal effects of body fat on PD, with multiple sex-specific body fat measures being involved. We performed Bayesian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39578713
DOI: 10.1111/cns.70132
PMCID: PMC11584348

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