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Article

Response of Blood Pressure to Renal Denervation Is Not Associated With Genetic Variants.

Hypertension (Dallas, Tex. : 1979) - 1 Jan 2025

Delles Christian, Schmieder Roland E, Daly Rónán, Kannenkeril Dennis, Bosch Agnes, Lauder Lucas, Kunz Michael, Böhm Michael, Hamilton Graham, Schmieder Raphael S, Schmid Axel, Herzyk Pawel, Mahfoud Felix

Abstract excerpt

BACKGROUND: Renal denervation lowers blood pressure (BP) in patients with uncontrolled hypertension. We conducted an unbiased genomic screen to identify genetic variants that may associate with BP response to renal denervation (RDN). METHODS: Patients (n=268) with uncontrolled resistant hypertension (baseline BP, 166±21/90±15 mm Hg) who underwent endovascular RDN using the Symplicity catheter (Medtronic, Inc,...

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Identifiers

PMID: 39569514
DOI: 10.1161/HYPERTENSIONAHA.124.23393
PMCID: PMC11654447

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ADD1
ADRB1
ADRB2
AGT
SCNN1A

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