Article
Polymorphisms of angiotensin-converting enzyme (ACE) and ACE2 are not associated with orthostatic blood pressure dysregulation in hypertensive patients.
Acta pharmacologica Sinica - 1 Sept 2009
Fan Xiao-han, Wang Yi-bo, Wang Hu, Sun Kai, Zhang Wei-li, Song Xiao-dong, Cheng Jing-zhou, Wu Hai-ying, Zhou Xiang-liang, Hui Ru-tai
Abstract excerpt
AIM: The genetic background of orthostatic blood pressure dysregulation remains poorly understood. Since the renin-angiotensin system plays an important role in blood pressure regulation and response to position change, we hypothesized that angiotensin-converting enzyme (ACE) and ACE2 genetic polymorphisms might contribute, at least partially, to orthostatic blood pressure dysregulation in hypertensive patients....
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