A polymorphism in the noradrenaline transporter gene is associated with increased blood pressure in patients with resistant hypertension.

doi:10.1097/HJH.0000000000001736

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A polymorphism in the noradrenaline transporter gene is associated with increased blood pressure in patients with resistant hypertension.

Journal of hypertension - 1 Jul 2018

Eikelis Nina, Marques Francine Z, Hering Dagmara, Marusic Petra, Head Geoffrey A, Walton Antony S, Lambert Elisabeth A, Esler Murray D, Sari Carolina I, Schlaich Markus P, Lambert Gavin W

Abstract excerpt

OBJECTIVES: Noradrenaline released from sympathetic nerves is rapidly inactivated via the action of the noradrenaline transporter (NET). We aimed to determine whether a single nucleotide polymorphism (SNP) in the NET gene, rs7194256, was associated with blood pressure and plasma noradrenaline concentration in patients with resistant hypertension. METHODS: Ninety-two consecutive patients with resistant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Pressure

Share to Drug Resistance

Share to Hypertension

Share to Norepinephrine

Share to Norepinephrine Plasma Membrane Transport Proteins

Share to Polymorphism, Single Nucleotide

Share to Systole

Source

Open in PubMed

Identifiers

PMID: 29677047
DOI: 10.1097/HJH.0000000000001736

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A polymorphism in the noradrenaline transporter gene is associated with increased blood pressure in patients with resistant hypertension.PMID 29677047Read ↗

Disorders of blood pressure regulation-role of catecholamine biosynthesis, release, and metabolism.Semantic proximity Read ↗

Resistant Hypertension Variants Link to Hyperaldosteronism and Potassium Levels.Semantic proximity Read ↗

Sympathetic Overactivation in the Resistant Hypertensive Phenotype: A Meta-Analysis of Published Studies.Semantic proximity Read ↗

Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humans.Semantic proximity Read ↗

Norepinephrine transporter gene (NET) polymorphism in patients with type 2 diabetes.Semantic proximity Read ↗

A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism.Semantic proximity Read ↗

Investigation of the correlation between norepinephrine transporter gene polymorphisms and essential hypertension.Semantic proximity Read ↗

Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine.Semantic proximity Read ↗

Genetic basis of clinical catecholamine disorders.Semantic proximity Read ↗

Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension.Semantic proximity Read ↗

ATP2B1 gene polymorphisms associated with resistant hypertension in the Japanese population.Semantic proximity Read ↗

The norepinephrine transporter in physiology and disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.