Article
Genome-wide study of resistant hypertension identified from electronic health records.
PloS one - 1 Jan 2017
Dumitrescu Logan, Ritchie Marylyn D, Denny Joshua C, El Rouby Nihal M, McDonough Caitrin W, Bradford Yuki, Ramirez Andrea H, Bielinski Suzette J, Basford Melissa A, Chai High Seng, Peissig Peggy, Carrell David, Pathak Jyotishman, Rasmussen Luke V, Wang Xiaoming, Pacheco Jennifer A, Kho Abel N, Hayes M Geoffrey, Matsumoto Martha, Smith Maureen E, Li Rongling, Cooper-DeHoff Rhonda M, Kullo Iftikhar J, Chute Christopher G, Chisholm Rex L, Jarvik Gail P, Larson Eric B, Carey David, McCarty Catherine A, Williams Marc S, Roden Dan M, Bottinger Erwin, Johnson Julie A, de Andrade Mariza, Crawford Dana C
Abstract excerpt
Resistant hypertension is defined as high blood pressure that remains above treatment goals in spite of the concurrent use of three antihypertensive agents from different classes. Despite the important health consequences of resistant hypertension, few studies of resistant hypertension have been conducted. To perform a genome-wide association study for resistant hypertension, we defined and identified cases of...
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