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Article

Genetic stability of Mycobacterium smegmatis under the stress of first-line antitubercular agents.

eLife - 20 Nov 2024

Molnár Dániel, Surányi Éva Viola, Trombitás Tamás, Füzesi Dóra, Hirmondó Rita, Toth Judit

Abstract excerpt

The sustained success of Mycobacterium tuberculosis as a pathogen arises from its ability to persist within macrophages for extended periods and its limited responsiveness to antibiotics. Furthermore, the high incidence of resistance to the few available antituberculosis drugs is a significant concern, especially since the driving forces of the emergence of drug resistance are not clear. Drug-resistant strains of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39565350
DOI: 10.7554/eLife.96695
PMCID: PMC11578590

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