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Article

Assessing the Impact of Bedaquiline, Clofazimine, and Linezolid on Mycobacterial Genome Integrity.

Biomolecules - 15 Nov 2024

Molnár Dániel, Surányi Éva Viola, Gálik Nikoletta, Tóth Judit, Hirmondó Rita

Abstract excerpt

Tuberculosis (TB) presents significant medical challenges, largely due to the genetic diversity of Mycobacterium tuberculosis, which enhances the resilience and resistance of the pathogen to first-line treatments. In response to the global rise of drug-resistant TB, second-line antitubercular drugs like bedaquiline (BDQ), linezolid (LZD), and clofazimine (CFZ) have become critical treatment options. Understanding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39595627
DOI: 10.3390/biom14111451
PMCID: PMC11591709

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