Article
Antibiotic resistance in mycobacteria.
Novartis Foundation symposium - 1 Jan 1998
Davies J
Abstract excerpt
Multiple drug resistance in mycobacteria compromises the use of antibiotics. Although the genetic and biochemical bases of antibiotic resistance in mycobacteria are largely understood, a number of questions remain to be addressed. This chapter discusses the potential roles of hypermutability and compensatory mutations in establishing stable resistant phenotypes in the pathogenic mycobacteria.
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