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Article

Germline pathogenic variants in prostate cancer.

Pathology, research and practice - 1 Dec 2024

Shakroo Yousif M, Seabury Charles A, Iczkowski Kenneth A, Nelson Kinloch, Qian Junqi, Ramnani Dharam M

Abstract excerpt

While most prostate cancer is sporadic, evidence suggests that a significant minority of cases have a hereditary component, and germline variants may play a role in this heritability. In this study, we investigated germline pathogenic variants in prostate cancer patients. All genetic variants were classified using the American College of Medical Genetics and Genomics/Association for Molecular Pathology 2015...

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PMID: 39541765
DOI: 10.1016/j.prp.2024.155718

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