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Article

Prevalence of Germline Variants in Prostate Cancer and Implications for Current Genetic Testing Guidelines

7 Feb 2019

Abstract excerpt

IMPORTANCE: Prostate cancer is the third leading cause of cancer-related death in men in the United States. Although serious, most of these diagnoses are not terminal. Inherited risk for prostate cancer is associated with aggressive disease and poorer outcomes, indicating a critical need for increased genetic screening to identify disease-causing variants that can pinpoint individuals at increased risk for...

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PMID: 30730552
DOI: 10.1001/jamaoncol.2018.6760

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