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Germline Pathogenic Variants in 7636 Japanese Patients With Prostate Cancer and 12 366 Controls

12 Jun 2019

Abstract excerpt

BACKGROUND: Genetic testing has been conducted in patients with prostate cancer (PCa) using multigene panels, but no centralized guidelines for genetic testing exist. To overcome this limitation, we investigated the demographic and clinical characteristics of patients with pathogenic variants. METHODS: We sequenced eight genes associated with hereditary PCa in 7636 unselected Japanese patients with PCa and 12 366...

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PMID: 31214711
DOI: 10.1093/jnci/djz124

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