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Article

Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales.

Pharmacogenetics and genomics - 1 Feb 2009

Sistonen Johanna, Fuselli Silvia, Palo Jukka U, Chauhan Neelam, Padh Harish, Sajantila Antti

Abstract excerpt

OBJECTIVES: CYP2C9, CYP2C19, and CYP2D6 belong to a subfamily of cytochrome P450 (CYP) enzymes, associated mainly with the metabolism of exogenous compounds in the human body. The genes coding for these enzymes are highly polymorphic and thus of major pharmacogenetic importance. By systematically retrieving data from the literature and genotyping new population samples, we aimed at describing the worldwide...

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PMID: 19151603
DOI: 10.1097/FPC.0b013e32831ebb30

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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