Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapeutic targets for lung cancer: genome-wide Mendelian randomization and colocalization analyses

28 Oct 2024

Abstract excerpt

Background: Lung cancer, categorized into non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), remains a significant global health challenge. The development of drug resistance and the heterogeneity of the disease necessitate the identification of novel therapeutic targets to improve patient outcomes. Methods: We conducted a genome-wide Mendelian randomization (MR) and colocalization analysis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Associations and Epidemiology
Share to Lung Cancer Research Studies
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39529882
DOI: 10.3389/fphar.2024.1441233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutic targets for lung cancer: genome-wide Mendelian randomization and colocalization analysesPMID 39529882Read ↗

Systematic proteome-wide Mendelian randomization using the human plasma proteome to identify therapeutic targets for lung adenocarcinoma.Semantic proximity Read ↗

Systematic Mendelian randomization using the human plasma proteome to identify therapeutic targets for lung adenocarcinomaSemantic proximity Read ↗

Systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for lung cancer.Semantic proximity Read ↗

Unveiling novel potential drug targets for lung cancer through Mendelian randomization analysis.Semantic proximity Read ↗

Druggable genome-wide Mendelian randomization integrating GWAS and eQTL/pQTL data identifies targets for lung squamous cell carcinomaSemantic proximity Read ↗

Bidirectional mendelian randomization and single-cell sequencing reveal T cell-mediated causal links between COPD and lung adenocarcinomaSemantic proximity Read ↗

Plasma proteometabolome in lung cancer: exploring biomarkers through bidirectional Mendelian randomization and colocalization analysisSemantic proximity Read ↗

Identification of promising lung cancer drug targets from human plasma proteins: Mendelian randomization, single-cell RNA sequencing analysisSemantic proximity Read ↗

Single-Cell Mendelian Randomization Identifies Cell-Type Specific Genetic Drivers of Lung Cancer SubtypesSemantic proximity Read ↗

Identification of breast cancer susceptibility genes via trans-ethnic Mendelian randomization and colocalization analyses.Semantic proximity Read ↗

Multidimensional bioinformatics perspective on smoking-linked driver genes and immune regulatory mechanisms in non-small cell lung cancerSemantic proximity Read ↗

Integrative Analysis of GWAS and Single-Cell eQTL Data Identifies Immune Cell-Type-Specific Genetic Signals Co-occurring in Inflammatory Diseases and Lung Cancer RiskSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.