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Peroxisome proliferator‑activated receptor γ coactivator‑1α in heart disease (Review)

4 Nov 2024

Abstract excerpt

Heart disease (HD) is a general term for various diseases affecting the heart. An increasing body of evidence suggests that the pathogenesis of HD is closely related to mitochondrial dysfunction. Peroxisome proliferator‑activated receptor γ coactivator‑1α (PGC‑1α) is a transcriptional coactivator that plays an important role in mitochondrial function by regulating mitochondrial biogenesis, energy metabolism and...

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PMID: 39513608
DOI: 10.3892/mmr.2024.13382

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