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Mitochondria and PGC-1α in Aging and Age-Associated Diseases

1 Jan 2011

Abstract excerpt

Aging is the most significant risk factor for a range of degenerative disease such as cardiovascular, neurodegenerative and metabolic disorders. While the cause of aging and its associated diseases is multifactorial, mitochondrial dysfunction has been implicated in the aging process and the onset and progression of age-associated disorders. Recent studies indicate that maintenance of mitochondrial function is...

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PMID: 21629705
DOI: 10.4061/2011/810619

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