Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Blossoming 20: The Energetic Regulator's Birthday Unveils its Versatility in Cardiac Diseases

1 Jan 2019

Abstract excerpt

The peroxisome proliferator-activated receptor γ (PPARγ) coactivator-1α (PGC-1α) was first identified in 1998 as a PGC-1 family member that regulates adaptive thermogenesis and mitochondrial function following cold exposure in brown adipose tissue. The PGC-1 family has drawn widespread attention over the past two decades as the energetic regulator. We recently summarized a review regarding PGC-1 signaling pathway...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Mitochondrial Function and Pathology
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30809287
DOI: 10.7150/thno.29130

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Blossoming 20: The Energetic Regulator's Birthday Unveils its Versatility in Cardiac DiseasesPMID 30809287Read ↗

PGC-1 Coactivators in Cardiac Development and DiseaseSemantic proximity Read ↗

PGC-1 coactivators: inducible regulators of energy metabolism in health and diseaseSemantic proximity Read ↗

Peroxisome proliferator‑activated receptor γ coactivator‑1α in heart disease (Review)Semantic proximity Read ↗

Metabolic reprogramming via PPARα signaling in cardiac hypertrophy and failure: From metabolomics to epigeneticsSemantic proximity Read ↗

PGC1s and Beyond: Disentangling the Complex Regulation of Mitochondrial and Cellular MetabolismSemantic proximity Read ↗

PGC-1 coactivators in the control of energy metabolismSemantic proximity Read ↗

Full-length transcriptomic analysis in murine and human heart reveals diversity of PGC-1α promoters and isoforms regulated distinctly in myocardial ischemia and obesitySemantic proximity Read ↗

Peroxisome proliferator-activated receptor-γ coactivator 1 α1 induces a cardiac excitation-contraction coupling phenotype without metabolic remodelling.Semantic proximity Read ↗

Full-length transcriptomic analysis in murine and human heart reveals diversity of PGC-1α promoters and isoforms regulated distinctly in myocardial ischemia and obesitySemantic proximity Read ↗

Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family in physiological and pathophysiological process and diseasesSemantic proximity Read ↗

Mechano-energetic uncoupling in hypertrophic cardiomyopathy: Pathophysiological mechanisms and therapeutic opportunitiesSemantic proximity Read ↗

Single-nucleus RNA sequencing defines adipose tissue subpopulations that contribute to Tibetan pig cold adaptationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.