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Article

Validation of the APOBEC3A-Mediated RNA Single Base Substitution Signature and Proposal of Novel APOBEC1, APOBEC3B, and APOBEC3G RNA Signatures.

Journal of molecular biology - 15 Dec 2024

Fixman Benjamin, Díaz-Gay Marcos, Qiu Connor, Margaryan Tamara, Lee Brian, Chen Xiaojiang S

Abstract excerpt

Mutational signature analysis gained significant attention for providing critical insights into the underlying mutational processes for various DNA single base substitution (SBS) signatures and their associations with different cancer types. Recently, RNA single base substitution (RNA-SBS) signatures were defined and described by decomposing RNA variants found in non-small cell lung cancer. Through statistical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39510348
DOI: 10.1016/j.jmb.2024.168854
PMCID: PMC11637894

Genes

APOBEC3A
APOBEC1
APOBEC3B
APOBEC3G

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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Validation of the APOBEC3A-Mediated RNA Single Base Substitution Signature and Proposal of Novel APOBEC1, APOBEC3B, and APOBEC3G RNA Signatures.PMID 39510348Read ↗

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