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Article

The implications of APOBEC3-mediated C-to-U RNA editing for human disease.

Communications biology - 4 May 2024

Van Norden Melissa, Falls Zackary, Mandloi Sapan, Segal Brahm H, Baysal Bora E, Samudrala Ram, Elkin Peter L

Abstract excerpt

Intra-organism biodiversity is thought to arise from epigenetic modification of constituent genes and post-translational modifications of translated proteins. Here, we show that post-transcriptional modifications, like RNA editing, may also contribute. RNA editing enzymes APOBEC3A and APOBEC3G catalyze the deamination of cytosine to uracil. RNAsee (RNA site editing evaluation) is a computational tool developed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38704509
DOI: 10.1038/s42003-024-06239-w
PMCID: PMC11069577

Genes

APOBEC3A
APOBEC3G

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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