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Natural Killer Cell Phenotypes and Clinical Outcomes in Pediatric Kidney Transplantation.

Pediatric transplantation - 1 Dec 2024

Kahan Riley H, Abraham Nader, Lee Hui-Jie, Ettenger Robert B, Grimm Paul C, Reed Elaine F, Reeves R Keith, Sarwal Minnie M, Stempora Linda L, Warshaw Barry L, Kirk Allan D, Martinez Olivia M, Chambers Eileen T

Abstract excerpt

BACKGROUND: Natural killer (NK) cells have gained recognition for playing an integral role in both alloimmunity and protective immunity, particularly viral infection control, in solid organ transplantation. Using data from the Clinical Trials in Organ Transplantation in Children (CTOTC) study entitled, "Immune Development in Pediatric Transplantation," (NCT00951353), we aimed to identify NK cell phenotypes that...

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PMID: 39508125
DOI: 10.1111/petr.14877

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