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An altered natural killer cell immunophenotype characterizes clinically severe pediatric RSV infection

9 Oct 2024

Abstract excerpt

Respiratory syncytial virus (RSV) infects nearly all children by 2 years of age and is a leading cause of pediatric hospitalizations. A subset of children with RSV infection (RSV + children) develop respiratory failure requiring intensive care, but immune mechanisms distinguishing severe pediatric RSV infection are not fully elucidated. Natural killer (NK) cells are key innate immune effectors of viral host...

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PMID: 39383246
DOI: 10.1126/scitranslmed.ado6606

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