Article
Relationship between antithymocyte globulin, T cell phenotypes, and clinical outcomes in pediatric kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Feb 2021
Shaw Brian I, Lee Hui-Jie, Chan Cliburn, Ettenger Robert, Grimm Paul, Pearl Meghan, Reed Elaine F, Robien Mark A, Sarwal Minnie, Stempora Linda, Warshaw Barry, Zhao Congwen, Martinez Olivia M, Kirk Allan D, Chambers Eileen T
Abstract excerpt
Depletional induction using antithymocyte globulin (ATG) reduces rates of acute rejection in adult kidney transplant recipients, yet little is known about its effects in children. Using a longitudinal cohort of 103 patients in the Immune Development in Pediatric Transplant (IMPACT) study, we compared T cell phenotypes after ATG or non-ATG induction. We examined the effects of ATG on the early clinical outcomes of...
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