Article

Mass cytometry analysis of the NK cell receptor-ligand repertoire reveals unique differences between dengue-infected children and adults

2020-07-29

Abstract excerpt

Dengue virus (DENV) is a significant cause of morbidity in many regions of the world, with children at the greatest risk of developing severe dengue. Natural killer (NK) cells, characterized by their ability to rapidly recognize and kill virally infected cells, are activated during acute DENV infection. However, their role in viral clearance versus pathogenesis has not been fully elucidated. Our goal was to profil...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4fb4a302-d4a2-5524-a731-98979676b723
DOI: 10.1101/2020.07.27.223339

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mass cytometry analysis of the NK cell receptor-ligand repertoire reveals unique differences between dengue-infected children and adultsDOI 10.1101/2020.07.27.223339Read

The alteration of NK cells phenotypes related to the functions and dengue disease outcomes.Semantic proximity Read

NKG2A discriminates natural killer cells with a suppressed phenotype in pediatric acute leukemia.Semantic proximity Read

Decoding NK Cell Subset Dysregulation in SARS-CoV-2 Infection: Phenotypic, Functional, and Transcriptomic Insights Into COVID-19 Pathogenesis.Semantic proximity Read

Global and cell type-specific immunological hallmarks of severe dengue progressionSemantic proximity Read

Disarming Cellular Alarm Systems—Manipulation of Stress-Induced NKG2D Ligands by Human HerpesvirusesSemantic proximity Read

An altered natural killer cell immunophenotype characterizes clinically severe pediatric RSV infectionSemantic proximity Read

Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cellsSemantic proximity Read

Natural Killer Cell Phenotypes and Clinical Outcomes in Pediatric Kidney Transplantation.Semantic proximity Read

Influence of human cytomegalovirus infection on the NK cell receptor repertoire in childrenSemantic proximity Read

Poorly cytotoxic terminally differentiated CD56negCD16pos NK cells accumulate in Kenyan children with Burkitt lymphomasSemantic proximity Read

Rapid NK cell differentiation in a population with near-universal human cytomegalovirus infection is attenuated by NKG2C deletions.Semantic proximity Read

Comprehensive Phenotyping of Human PB NK Cells by Flow Cytometry.Semantic proximity Read