Exploring the Prevalence and Prognostic Impact of Wilms Tumor 1 Exon 7 Mutation Status with Combinations of FLT3-ITD and NPM1 Mutations as Potential Molecular Biomarkers in Acute Myeloid Leukemia Patients with Normal Cytogenetics.

doi:10.31557/APJCP.2024.25.10.3463

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Exploring the Prevalence and Prognostic Impact of Wilms Tumor 1 Exon 7 Mutation Status with Combinations of FLT3-ITD and NPM1 Mutations as Potential Molecular Biomarkers in Acute Myeloid Leukemia Patients with Normal Cytogenetics.

Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2024

John Anitha Geetha Raj, Radhakrishnan Chandraprabha Vineetha, Padmakumar Devipriya, Mohanan Sreelatha Mahitha, Padmakumar Amritha, Gopinath Preethi, Thampirajan Vimala Devi Akhila Raj, Lathika Surendran Suraj, Narayanan Geetha, Sreedharan Hariharan, Mohanan Nair Jagathnath Krishna Kumarapillai

Abstract excerpt

AIM: This study explores the prognostic impact of FLT3-ITD, NPM1, and WT1 mutations both independently and in combination in Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) patients as they exhibit varying clinical outcomes. METHODS: 150 CN-AML patients were selected to assess the prevalence and prognostic significance of WT1 mutations in combination with FLT3-ITD and NPM1 status using polymerase chain...

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PMID: 39471012
DOI: 10.31557/APJCP.2024.25.10.3463

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Exploring the Prevalence and Prognostic Impact of Wilms Tumor 1 Exon 7 Mutation Status with Combinations of FLT3-ITD and NPM1 Mutations as Potential Molecular Biomarkers in Acute Myeloid Leukemia Patients with Normal Cytogenetics.PMID 39471012Read ↗

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