Prevalence and Prognostic Impact of Wilms' Tumor 1 (WT1) Gene, Including SNP rs16754 in Cytogenetically Normal Acute Myeloblastic Leukemia (CN-AML): An Iranian Experience.

doi:10.1016/j.clml.2015.11.017

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Prevalence and Prognostic Impact of Wilms' Tumor 1 (WT1) Gene, Including SNP rs16754 in Cytogenetically Normal Acute Myeloblastic Leukemia (CN-AML): An Iranian Experience.

Clinical lymphoma, myeloma & leukemia - 1 Mar 2016

Toogeh Gholamreza, Ramzi Mani, Faranoush Mohammad, Amirizadeh Naser, Haghpanah Sezaneh, Moghadam Mohammad, Cohan Nader

Abstract excerpt

BACKGROUND: The aim of this study was to evaluate the effect of Wilms' tumor 1 (WT1) gene mutations in adult cytogenetically normal acute myeloblastic leukemia (CN-AML) patients on survival and clinical outcome. PATIENTS AND METHODS: A total of 88 untreated Iranian adult patients with CN-AML were selected as a study group. Exons 7 (including the SNP rs16754), 8, and 9 as a WT1 gene hotspot region were evaluated...

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PMID: 26725263
DOI: 10.1016/j.clml.2015.11.017

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