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Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: a study of the German-Austrian AML Study Group.

Blood - 7 May 2009

Gaidzik Verena Ingeborg, Schlenk Richard Friedrich, Moschny Simone, Becker Annegret, Bullinger Lars, Corbacioglu Andrea, Krauter Jürgen, Schlegelberger Brigitte, Ganser Arnold, Döhner Hartmut, Döhner Konstanze

Abstract excerpt

To evaluate the incidence and clinical impact of WT1 gene mutations in younger adult patients with cytogenetically normal acute myeloid leukemia (CN-AML), sequencing of the complete coding region was performed in diagnostic samples from 617 patients who were treated on 3 German-Austrian AML Study Group protocols. WT1 mutations were identified in 78 (12.6%) of the 617 patients; mutations clustered in exon 7 (54 of...

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Identifiers

PMID: 19221039
DOI: 10.1182/blood-2008-10-183392

Genes

FLT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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