Article
Identification of 8-Digit HLA-A, -B, -C, and -DRB1 Allele and Haplotype Frequencies in Koreans Using the One Lambda AllType Next-Generation Sequencing Kit.
Annals of laboratory medicine - 1 May 2021
Choe Wonho, Chae Jeong-Don, Yang John Jeongseok, Hwang Sang-Hyun, Choi Sung-Eun, Oh Heung-Bum
Abstract excerpt
BACKGROUND: Recent studies have successfully implemented next-generation sequencing (NGS) in HLA typing. We performed HLA NGS in a Korean population to estimate HLA-A, -B, -C, and -DRB1 allele and haplotype frequencies up to an 8-digit resolution, which might be useful for an extended application of HLA results. METHODS: A total of 128 samples collected from healthy unrelated Korean adults, previously subjected...
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