Article
Distribution of MICA haplotypes in a Chinese Han population.
Human immunology - 1 Jan 2012
Xu Xiuzhang, Xia Wenjie, Tian Linwei, Chen Yangkai, Ding Haoqiang, Shao Yuan, Deng Jing, Wang Jiali, Huang Yingfeng, Santoso Sentot, Fu Yongshui, Ye Xin
Abstract excerpt
The MICA gene encodes nonclassical major histocompatibility complex class I molecules, centromeric to HLA-B and telomeric to HLA-DRB1. The MICA genes are polymorphic. The immune response against MICA may correlate with a decrease in graft survival after transplantation. However, data on the frequency of MICA polymorphisms in different populations are limited. In this study, we determined MICA allelic frequencies...
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