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High-Resolution Eight-Digit Human Leukocyte Antigen-A, -B, -C, and -DRB1 Allele and Haplotype Frequencies in South Koreans Using Next-Generation Sequencing.

Annals of laboratory medicine - 1 Jul 2026

Lee Howon, Lee Gun Dong, Jekarl Dong Wook, Kim Myungshin, Kim Yonggoo

Abstract excerpt

Background: Data on human leukocyte antigen (HLA) typing using modern high-resolution methods are increasingly needed. Previous HLA studies in Korea were limited by small sample sizes or low-resolution data. We analyzed high-resolution (eight-digit) HLA data obtained through next-generation sequencing from healthy volunteers from Korea registered for hematopoietic stem cell transplantation, providing a...

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Identifiers

PMID: 41407397
DOI: 10.3343/alm.2025.0393
PMCID: PMC13259942

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