Article
Distributions of HLA-A, -B, and -DRB1 alleles typed by amplicon-based next generation sequencing in Korean volunteer donors for unrelated hematopoietic stem cell transplantation.
HLA - 1 Feb 2021
Baek In-Cheol, Choi Eun-Jeong, Shin Dong-Hwan, Kim Hyoung-Jae, Choi Haeyoun, Kim Tai-Gyu
Abstract excerpt
HLA genes play a pivotal role for successful hematopoietic stem cell transplantation (HSCT). There is an increasing need for sophisticated screening of donor HLA genotypes for unrelated HSCT. Next generation sequencing (NGS) has emerged as an alternative for classical Sanger sequence for HLA typi...
Topics
- Alleles
- Gene Frequency
- HLA-A Antigens
- HLA-B Antigens
- HLA-DRB1 Chains
- Haplotypes
- Hematopoietic Stem Cell Transplantation
- High-Throughput Nucleotide Sequencing
- Histocompatibility Testing
- Humans
- Republic of Korea
- Tissue Donors