Article

Characterization of DNA hydroxymethylation in hypothalamus of elderly mice with postoperative cognitive dysfunction

2018-12-06

Abstract excerpt

Postoperative cognitive dysfunction (POCD) is a common syndrome with perioperative cerebral damage in elderly patients, displaying cognitive impairment and memory loss. Current studies revealed that anesthesia is one of the important causes for POCD occurrence. Recently, Ubiquitin-like with PHD and Ring Figner Domains 2 (Uhrf2) has been reported to play a crucial role in regulating DNA methylation and hydroxymethy...

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Literature Corpus work: 8086d120-b74e-5e5f-baa0-346ecb07032b
DOI: 10.1101/488007

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