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Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane

27 Nov 2024

Abstract excerpt

Introduction: Whether repeated inhalation of sevoflurane during the neonatal period causes long-term learning and memory impairments in humans is unclear. Some recent investigations have indicated that general anesthesia drugs affect histone methylation modification and may further affect learning and memory ability. This study aimed to explore the role and mechanism of histone methylation in long-term cognitive...

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PMID: 39664113
DOI: 10.3389/fnmol.2024.1459358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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