Article
DNA polymorphisms in inflammatory and endocrine signals linked to frailty are also associated with obesity: data from the FRASNET cohort.
Frontiers in endocrinology - 1 Jan 2024
Damanti Sarah, Citterio Lorena, Zagato Laura, Brioni Elena, Magnaghi Cristiano, Simonini Marco, De Lorenzo Rebecca, Ruggiero Mariapia, Santoro Simona, Senini Eleonora, Messina Marco, Vitali Giordano, Manunta Paolo, Manfredi Angelo Andrea, Lanzani Chiara, Rovere Querini Patrizia
Abstract excerpt
Background: Obesity and frailty are prevalent geriatric conditions that share some pathophysiological mechanisms and are associated with adverse clinical outcomes. The relationship between frailty, obesity, and polymorphism remains inadequately explored. Single nucleotide polymorphisms (SNPs) offer insights into genetic predispositions that may influence the development of both frailty and obesity. Methods: We...
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