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Article

Genetic insights into aging: Obesity's impact on frailty risk uncovered.

Medicine - 2 Jan 2026

Wang Yongguang, Zhou Jinlei, Zhao Tingxiao, Wang Qi

Abstract excerpt

Frailty is an age-associated condition characterized by a state of vulnerability that compromises the quality of life and independence of older adults. To date, no studies have employed Mendelian randomization (MR) to investigate the causal relationship between obesity and frailty risk. Therefore, this study utilized a two-sample MR approach to elucidate the potential causal link between obesity and frailty. A...

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Identifiers

PMID: 41496051
DOI: 10.1097/MD.0000000000046406
PMCID: PMC12778282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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