Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal hematopoiesis in cardiovascular aging: Insights from the verona heart study.

GeroScience - 1 Apr 2025

Kwiatkowska Katarzyna Malgorzata, Martinelli Nicola, Bertamini Luca, De Fanti Sara, Olivieri Oliviero, Sala Claudia, Castellani Gastone, Xumerle Luciano, Zago Elisa, Busti Fabiana, Giuliani Cristina, Garagnani Paolo, Girelli Domenico

Abstract excerpt

Clonal hematopoiesis of indeterminate potential (CHIP), marked by the accumulation of somatic mutations in hematopoietic stem cells, significantly elevates the risk of all-cause mortality, mainly due to cardiovascular events. Therefore, investigating this pathophysiological phenomenon is crucial for understanding cardiovascular aging and enhancing both health span and lifespan. In the present study, we examined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Clonal Hematopoiesis

Share to Coronary Artery Disease

Share to DNMT3A gene

Share to SF3B1 gene

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 39460851
DOI: 10.1007/s11357-024-01367-x
PMCID: PMC11979038

Genes

CAD
ASXL1
DNMT3A
IDH2
JAK2
TET2
SF3B1
TP53
U2AF1
IDH1
PPM1D
SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal hematopoiesis in cardiovascular aging: Insights from the verona heart study.PMID 39460851Read ↗

Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease.Semantic proximity Read ↗

Genomic Aging, Clonal Hematopoiesis, and Cardiovascular Disease.Semantic proximity Read ↗

Long-term longitudinal analysis of 4,187 participants reveals insights into determinants of clonal hematopoiesis.Semantic proximity Read ↗

Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart FailureSemantic proximity Read ↗

Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure.Semantic proximity Read ↗

Somatic Mutations and Clonal Hematopoiesis as Drivers of Age-Related Cardiovascular Risk.Semantic proximity Read ↗

Clonal Hematopoiesis of Indeterminate Potential: an Expanding Genetic Cause of Cardiovascular Disease.Semantic proximity Read ↗

Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease.Semantic proximity Read ↗

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.Semantic proximity Read ↗

Clonal Hematopoiesis and Risk of Progression of Heart Failure With Reduced Left Ventricular Ejection Fraction.Semantic proximity Read ↗

CHIP In cardiovascular and immune ageing.Semantic proximity Read ↗

Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.