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Article

Genomic Aging, Clonal Hematopoiesis, and Cardiovascular Disease.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2023

Natarajan Pradeep

Abstract excerpt

Chronologic age is the dominant risk factor for coronary artery disease but the features of aging promoting coronary artery disease are poorly understood. Advances in human genetics and population-based genetic profiling of blood cells have uncovered the surprising role of age-related subclinical leukemogenic mutations in blood cells, termed "clonal hematopoiesis of indeterminate potential," in coronary artery...

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Identifiers

PMID: 36353993
DOI: 10.1161/ATVBAHA.122.318181
PMCID: PMC9780188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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